Explore the latest in neurology, including recent guidelines and advances in management of stroke, dementia, demyelinating disease, and more.
A woman who had immigrated from Guatemala 1 year prior developed headache, photophobia, vomiting, somnolence, and confusion but no focal neurologic deficits. Brain CT showed ventriculomegaly, hydrocephalus, and cerebral edema, while brain MRI showed a nonenhancing lesion obstructing the aqueduct of Sylvius that moved to the fourth ventricle with hydrocephalus resolution on repeat imaging 5 days later. What is the diagnosis and what would you do next?
This systematic review and network meta-analysis evaluates which operation for cubital tunnel syndrome is associated with the best chance of symptomatic cure and lowest risk of complications.
This cross-sectional analysis examines the representation of female medical school graduates in residency programs by specialty using aggregate data from the Canadian Residency Matching Service database.
This randomized clinical trial examines the use of clinical neurophysiological metrics of excitability as pharmacodynamic biomarkers in individuals with amyotrophic lateral sclerosis.
This cross-sectional study examines associations among brain volume, brain network connectivity, and neurocognitive test performance in survivors of childhood acute lymphoblastic leukemia treated with chemotherapy only.
A 40-year-old woman with dizziness and imbalance, a petechial rash on her palms and soles, and a right thumbnail splinter hemorrhage had acute right cerebellar infarcts with a left atrial mass on CT angiogram. What is the diagnosis and what would you do next?
This cross-sectional study examines the association between leisure time physical activity and measures of brain health assessed by magnetic resonance imaging in older adults.
A 68-year-old woman has a 3-week history of progressive eye redness and discomfort unresponsive to topical treatment. What would you do next?
This Viewpoint uses clinical observations of the natural course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to propose 3 phases of illness: acute infection (what people commonly refer to with the COVID-19 designation); postacute hyperinflammatory illness (referred to clinically as multisystem inflammatory syndrome); and late inflammatory sequelae, manifest as enduring cardiac, neurological, and psychological symptoms.
This Special Communication offers the authors’ thoughts on new approaches to psychiatric research using animal models and other techniques.
This cohort study investigates whether a bidirectional association exists between daily physical activity and postconcussion symptoms among youths with physician-confirmed concussion.
This study examines the association of blood lead levels in childhood with MRI measures of brain integrity as well as cognitive function assessments at age 45 years in a New Zealand birth cohort.
This cohort study examines patient characteristics associated with recovery time in pediatric patients with mild traumatic brain injury treated at concussion specialty clinics.
A 42-year-old woman presented with clinical features of microcephaly, short stature, intellectual disability, severe degree of scoliosis, gait abnormality, and encephalopathy. What is your diagnosis?
This case report describes a man who experienced a hyperacute spontaneous intracerebral hemorrhage when a computed tomography scan was underway.
This study evaluates whole-exome sequencing as a diagnostic tool in a cohort of neurosurgically treated congenital hydrocephalus probands.
This systematic review and meta-analysis assesses the likelihood that methodological biases in cohort studies and case-control studies, rather than a common etiology, explain the inverse association between cancer and subsequent Alzheimer disease incidence among older adults.
This cross-sectional study assesses the association between hearing, vision, or dual sensory impairment and patient satisfaction with quality of care, communication from health professionals, and access to care among a nationally representative sample of Medicare beneficiaries.
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