[Skip to Content]
Sign In
Individual Sign In
Create an Account
Institutional Sign In
OpenAthens Shibboleth
Purchase Options:
[Skip to Content Landing]

Year

Day

November 23, 2020
Research Letter

Psychological Distress and COVID-19–Related Stressors Reported in a Longitudinal Cohort of US Adults in April and July 2020

Abstract Full Text
free access
JAMA. Published online November 23, 2020. doi:10.1001/jama.2020.21231

This study used an online survey to assess how psychological distress has changed over the course of the coronavirus disease 2019 (COVID-19) pandemic from April to July 2020.

JAMA Insights

Diagnosis, Management, and Pathophysiology of Arterial and Venous Thrombosis in COVID-19

Abstract Full Text
free access
JAMA. Published online November 23, 2020. doi:10.1001/jama.2020.23422

This JAMA Insights review summarizes the pathophysiology underlying the thrombotic diathesis characteristic of acute SARS-CoV-2 infection and current recommendations for the prevention, diagnosis, and management of the most common thrombotic complications in COVID-19, including acute myocardial infarction (AMI), ischemic stroke, and venous thromboembolism (VTE).

November 20, 2020
Viewpoint

Older Adults and the Mental Health Effects of COVID-19

Abstract Full Text
free access has audio
JAMA. Published online November 20, 2020. doi:10.1001/jama.2020.21753

This Viewpoint summarizes evidence suggesting that, counter to expectation, older adults as a group may be more resilient to the anxiety, depression, and stress-related mental health disorders characteristic of younger populations during the COVID-19 pandemic.

JAMA Clinical Challenge

A Patient With Dizziness, Chest Pain, Rash, and Nail Changes

Abstract Full Text
has active quiz
JAMA. Published online November 20, 2020. doi:10.1001/jama.2020.15176

A 40-year-old woman with dizziness and imbalance, a petechial rash on her palms and soles, and a right thumbnail splinter hemorrhage had acute right cerebellar infarcts with a left atrial mass on CT angiogram. What is the diagnosis and what would you do next?

November 19, 2020
Viewpoint

Improving Care for Heart Failure With Reduced Ejection Fraction—A Potential Polypill-Based Strategy

Abstract Full Text
free access
JAMA. Published online November 19, 2020. doi:10.1001/jama.2020.21395

This Viewpoint proposes that a polypill combination of a β-blocker, renin angiotensin inhibitor, mineralocorticoid receptor antagonist, and sodium-glucose cotransporter 2 inhibitor might be the most efficient way to deliver guideline-directed HFrEF therapy, and proposes a research roadmap to design and evaluate the pill and implementation strategies for getting it to patients.

How to Leverage the Medicare Program for a COVID-19 Vaccination Campaign

Abstract Full Text
free access has active quiz
JAMA. Published online November 19, 2020. doi:10.1001/jama.2020.22720

This Viewpoint proposes that Medicare claims data could inform the rollout of a COVID-19 vaccination program in the US, including notifying beneficiaries of their risk and prioritization and supporting efforts to allocate the vaccine and monitor its uptake, immunogenicity, and safety.

November 18, 2020
Viewpoint

A Proposed Framework and Timeline of the Spectrum of Disease Due to SARS-CoV-2 Infection: Illness Beyond Acute Infection and Public Health Implications

Abstract Full Text
free access has active quiz
JAMA. Published online November 18, 2020. doi:10.1001/jama.2020.22717

This Viewpoint uses clinical observations of the natural course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to propose 3 phases of illness: acute infection (what people commonly refer to with the COVID-19 designation); postacute hyperinflammatory illness (referred to clinically as multisystem inflammatory syndrome); and late inflammatory sequelae, manifest as enduring cardiac, neurological, and psychological symptoms.

Editorial

JAMA Health Forum—A New JAMA Network Specialty Journal

Abstract Full Text
free access
JAMA. Published online November 18, 2020. doi:10.1001/jama.2020.23376
Medical News & Perspectives

Looking to Long-term Survivors for Improved Pancreatic Cancer Treatment

Abstract Full Text
free access
JAMA. Published online November 18, 2020. doi:10.1001/jama.2020.21717

This Medical News article examines how studying the characteristics of long-term pancreatic cancer survivors might improve treatment and boost survival for others who have the disease

November 16, 2020
Viewpoint

COVID-19, Decarceration, and the Role of Clinicians, Health Systems, and Payers: A Report From the National Academy of Sciences, Engineering, and Medicine

Abstract Full Text
free access has active quiz
JAMA. Published online November 16, 2020. doi:10.1001/jama.2020.22109

This Viewpoint summarizes a National Academy of Sciences, Engineering, and Medicine (NASEM) consensus panel report recommending ways to reduce populations in prisons and jails as a means to mitigate SARS-CoV-2 transmission and the roles clinicians, health systems, and insurers can play in in process.

November 15, 2020
Original Investigation

Effect of High-Dose Omega-3 Fatty Acids vs Corn Oil on Major Adverse Cardiovascular Events in Patients at High Cardiovascular Risk: The STRENGTH Randomized Clinical Trial

Abstract Full Text
has audio
JAMA. Published online November 15, 2020. doi:10.1001/jama.2020.22258

This randomized trial examines the effects on cardiovascular outcomes of a carboxylic acid formulation of EPA and DHA (omega-3 CA) with documented favorable effects on lipid and inflammatory markers in patients with atherogenic dyslipidemia and high cardiovascular risk.

Editorial

Effects of Omega-3 Fatty Acids on Major Adverse Cardiovascular Events: What Matters Most: the Drug, the Dose, or the Placebo?

Abstract Full Text
JAMA. Published online November 15, 2020. doi:10.1001/jama.2020.22387
Editor's Note

Do Omega-3 Fatty Acids Benefit Health?

Abstract Full Text
free access
JAMA. Published online November 15, 2020. doi:10.1001/jama.2020.22898
November 13, 2020
Original Investigation

Association Between Adherence to Fractional Flow Reserve Treatment Thresholds and Major Adverse Cardiac Events in Patients With Coronary Artery Disease

Abstract Full Text
JAMA. Published online November 13, 2020. doi:10.1001/jama.2020.22708

This cohort study assesses adherence to evidence-based fractional flow reserve (FFR) thresholds for percutaneous coronary intervention in Canada between 2013 and 2018, and associations of percutaneous coronary intervention with major adverse clinical outcomes for patients with FFR measures above and beneath ischemic thresholds.

Viewpoint

Hospital-Acquired SARS-CoV-2 Infection: Lessons for Public Health

Abstract Full Text
free access has active quiz
JAMA. Published online November 13, 2020. doi:10.1001/jama.2020.21399

This Viewpoint reviews the rare incidence of nosocomial SARS-CoV-2 infection and discusses ways it can be minimized, including use of surgical masks, proper ventilation, physical distancing, eye protection, regular testing, and the availability of sick leave for health care workers.

The Need for More and Better Testing for COVID-19

Abstract Full Text
free access has active quiz
JAMA. Published online November 13, 2020. doi:10.1001/jama.2020.21694

This Viewpoint proposes criteria for more effective COVID-19 testing strategies to manage population transmission, including use of rapid antigen tests and self-administered nasal and salivary tests, emphasizing that more effective testing alone cannot control the pandemic without continued public health interventions, such as mask wearing, physical distancing, and avoidance of large gatherings.

Editorial

Physiology-Based Revascularization Decisions and Improved Clinical Outcomes Following Percutaneous Coronary Interventions

Abstract Full Text
JAMA. Published online November 13, 2020. doi:10.1001/jama.2020.22998
November 12, 2020
Preliminary Communication

Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19: A Randomized Clinical Trial

Abstract Full Text
free access has active quiz
JAMA. Published online November 12, 2020. doi:10.1001/jama.2020.22760

This randomized trial compares the effects of fluvoxamine, a selective serotonin reuptake inhibitor with immunomodulatory effects vs placebo on a composite of dyspnea or pneumonia and oxygen desaturation among adult outpatients with polymerase chain reaction–confirmed mild coronavirus disease 2019 (COVID-19) illness.

Editor's Note

COVID-19 Infection—Preventing Clinical Deterioration

Abstract Full Text
free access has active quiz
JAMA. Published online November 12, 2020. doi:10.1001/jama.2020.21720
November 11, 2020
Viewpoint

The Challenges Ahead With Monoclonal Antibodies: From Authorization to Access

Abstract Full Text
free access has active quiz
JAMA. Published online November 11, 2020. doi:10.1001/jama.2020.21872

This Viewpoint discusses questions about clinical indication, supply, distribution, and cost and coverage that will need to be resolved if monoclonal antibodies are be granted Emergency Use Authorization or licensure and become available as treatment for COVID-19.

Therapy for Early COVID-19: A Critical Need

Abstract Full Text
free access has active quiz
JAMA. Published online November 11, 2020. doi:10.1001/jama.2020.22813

In this Viewpoint, Fauci and NIAID colleagues review leading candidates for treatment of mild to moderate coronavirus disease 2019 (COVID-19) to prevent disease progression and longer-term complications, including emerging antiviral drugs, immune-modulating agents, and antibody-based therapies, and the challenges of developing randomized trials to rapidly evaluate the safety and efficacy of each.

Medical News & Perspectives

Younger Adults Caught in COVID-19 Crosshairs as Demographics Shift

Abstract Full Text
free access has active quiz has audio
JAMA. Published online November 11, 2020. doi:10.1001/jama.2020.21913

This Medical News article discusses the health implications of severe acute respiratory syndrome coronavirus 2 infection among young and middle-aged adults.

November 9, 2020
Original Investigation

Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial

Abstract Full Text
free access has active quiz has audio
JAMA. Published online November 9, 2020. doi:10.1001/jama.2020.22240

This randomized trial compares the effects of hydroxychloroquine vs placebo on clinical status at 14 days (home, requiring noninvasive or invasive ventilation or extracorporeal membrane oxygenation, hospitalized, died) among adults hospitalized with coronavirus disease 2019 (COVID-19).

Editorial

Misguided Use of Hydroxychloroquine for COVID-19: The Infusion of Politics Into Science

Abstract Full Text
free access has active quiz
JAMA. Published online November 9, 2020. doi:10.1001/jama.2020.22389
November 6, 2020
JAMA Clinical Guidelines Synopsis

Recommendations for Follow-up Colonoscopy After Polypectomy

Abstract Full Text
has audio
JAMA. Published online November 6, 2020. doi:10.1001/jama.2020.15001

This JAMA Clinical Guidelines Synopsis summarizes the US Multi-Society Task Force on Colorectal Cancer’s 2020 recommendations for follow-up after colonoscopy and polypectomy.

November 2, 2020
Viewpoint

Science Denial and COVID Conspiracy Theories: Potential Neurological Mechanisms and Possible Responses

Abstract Full Text
free access has active quiz
JAMA. Published online November 2, 2020. doi:10.1001/jama.2020.21332

This Viewpoint discusses possible parallels between the distortion in sensory information and faulty monitoring of ideas characteristic of some patients with neurodegenerative diseases (dementia with Lewy bodies and Capgras syndrome, frontotemporal dementia) and the creation and maintenance of false conspiratorial beliefs about the COVID-19 pandemic in healthy populations that has hobbled an effective national response in the US.

JAMA Insights

Clinical Update

Preparing for the 2020-2021 Influenza Season

Abstract Full Text
has audio
JAMA. Published online November 2, 2020. doi:10.1001/jama.2020.21849

This JAMA Insights Clinical Update discusses the importance of established influenza prevention and control measures, including influenza vaccination and antiviral treatment, as the Global North enters its first influenza season in the COVID-19 pandemic.

JAMA Patient Page

High-risk Groups for Influenza Complications

Abstract Full Text
free access has audio
JAMA. Published online November 2, 2020. doi:10.1001/jama.2020.21869

This JAMA Patient Page describes the groups of people who are at high risk of complications from influenza infection, how to reduce risk through vaccination, and steps high-risk people should take if they develop influenza symptoms.

×