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January 2021, Vol 157, No. 1, Pages 19-124

Editorial

Ongoing Concerns Regarding Finasteride for the Treatment of Male-Pattern Androgenetic Alopecia

Abstract Full Text
JAMA Dermatol. 2021;157(1):25-26. doi:10.1001/jamadermatol.2020.3384

Economics of Teledermatology—Does the Math Add Up?

Abstract Full Text
JAMA Dermatol. 2021;157(1):27-28. doi:10.1001/jamadermatol.2020.4067
Original Investigation

Investigation of Suicidality and Psychological Adverse Events in Patients Treated With Finasteride

Abstract Full Text
JAMA Dermatol. 2021;157(1):35-42. doi:10.1001/jamadermatol.2020.3385

This case-control study investigates the association of suicidality (ideation, attempt, and completed suicide) and psychological adverse events (depression and anxiety) with use of finasteride in a global database.

Association of Secukinumab Treatment With Tuberculosis Reactivation in Patients With Psoriasis, Psoriatic Arthritis, or Ankylosing Spondylitis

Abstract Full Text
open access
JAMA Dermatol. 2021;157(1):43-51. doi:10.1001/jamadermatol.2020.3257

This pooled cohort study evaluates the safety of newer biological agents for the treatment of tuberculosis infection and activation in patients with psoriasis, psoriatic arthritis, and ankylosing spondylitis.

Cost Minimization Analysis of a Teledermatology Triage System in a Managed Care Setting

Abstract Full Text
has audio
JAMA Dermatol. 2021;157(1):52-58. doi:10.1001/jamadermatol.2020.4066

This cost minimization analysis compares the organization-wide cost of managing newly referred dermatology patients within a teledermatology triage system vs a conventional dermatology care model.

Assessment of Age, Period, and Birth Cohort Effects and Trends in Merkel Cell Carcinoma Incidence in the United States

Abstract Full Text
has active quiz
JAMA Dermatol. 2021;157(1):59-65. doi:10.1001/jamadermatol.2020.4102

This cross-sectional study uses data from the Surveillance, Epidemiology, and End Results Program to evaluate the associations of patient age, calendar period of diagnosis, and birth cohort with the increasing incidence of Merkel cell carcinoma and provide new incidence projections to 2030.

Randomized Trial Replication Using Observational Data for Comparative Effectiveness of Secukinumab and Ustekinumab in Psoriasis: A Study From the British Association of Dermatologists Biologics and Immunomodulators Register

Abstract Full Text
open access
JAMA Dermatol. 2021;157(1):66-73. doi:10.1001/jamadermatol.2020.4202

This comparative effectiveness research study examines observational data from the British Association of Dermatologists Biologics and Immunomodulators Register and compares them with clinical trial data to determine the effectiveness of 2 psoriasis medications.

Brief Report

Tofacitinib for the Treatment of Nail Lesions and Palmoplantar Pustulosis in Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome

Abstract Full Text
JAMA Dermatol. 2021;157(1):74-78. doi:10.1001/jamadermatol.2020.3095

This case series study examines the use of tofacitinib for treating nail involvement in Chinese women with synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome.

Incidence of New Primary Cutaneous Melanoma in Patients With Metastatic Melanoma Treated With Immune Checkpoint Inhibitors: A Single-Center Cohort Study

Abstract Full Text
JAMA Dermatol. 2021;157(1):79-83. doi:10.1001/jamadermatol.2020.3671

This observational cohort study assesses the incidence of new cutaneous melanoma in patients treated with ipilimumab, nivolumab, and/or pembrolizumab for metastatic melanoma.

Association of Mohs Micrographic Surgery vs Wide Local Excision With Overall Survival Outcomes for Patients With Melanoma of the Trunk and Extremities

Abstract Full Text
JAMA Dermatol. 2021;157(1):84-89. doi:10.1001/jamadermatol.2020.3950

This retrospective cohort study analyzes data from the National Cancer Database regarding outcomes of Mohs micrographic surgery versus wide local excision in treatment of melanomas that occur in the trunk and extremities.

Low-Dose Total Skin Electron Beam Therapy as Part of a Multimodality Regimen for Treatment of Sézary Syndrome: Clinical, Immunologic, and Molecular Analysis

Abstract Full Text
JAMA Dermatol. 2021;157(1):90-95. doi:10.1001/jamadermatol.2020.3958

This case series discusses 3 patients with Sézary syndrome who were treated with low-dose total skin electron beam therapy as part of a multimodality systemic regimen.

Consensus Statement

Consensus Statement for the Management and Treatment of Port-Wine Birthmarks in Sturge-Weber Syndrome

Abstract Full Text
JAMA Dermatol. 2021;157(1):98-104. doi:10.1001/jamadermatol.2020.4226

This consensus statement presents recommendations for treatment of port-wine birthmarks.

Images in Dermatology

Trichodysplasia Spinulosa in a Kidney Transplant Recipient

Abstract Full Text
JAMA Dermatol. 2021;157(1):105. doi:10.1001/jamadermatol.2020.3986

This case report describes a kidney transplant recipient with pink follicular papules with central white spicules on her face, ears, and extremities.

Erythema Ab Igne

Abstract Full Text
JAMA Dermatol. 2021;157(1):106. doi:10.1001/jamadermatol.2020.3995

This case report describes a teenage girl with a medical history of an eating disorder who presented with livedolike skin changes on the abdomen and was subsequently diagnosed with erythema ab igne.

JAMA Dermatology Clinicopathological Challenge

Rapidly Progressive Stiffness and Nodularity of Both Hands in a Middle-aged Woman

Abstract Full Text
has active quiz
JAMA Dermatol. 2021;157(1):107-108. doi:10.1001/jamadermatol.2020.4386

A middle-aged woman presented with rapidly progressive redness and stiffness of both hands, accompanied by 2 months of multiple finger joint and right shoulder pain. What is your diagnosis?

Reddish-Brown Hematomalike Annular Plaque in a Healthy Patient’s Axilla

Abstract Full Text
has active quiz
JAMA Dermatol. 2021;157(1):109-110. doi:10.1001/jamadermatol.2020.4563

A healthy man in his 50s presents with an asymptomatic, reddish hematomalike plaque with a brownish peripheral border in his left axilla, and a biopsy is positive for CD31, CD34, and D2-40 and negative for Wilms tumor 1. What is your diagnosis?

Research Letter

Diagnosis, Clinical Features, and Management of Patients With Granulomatous Cheilitis

Abstract Full Text
JAMA Dermatol. 2021;157(1):112-114. doi:10.1001/jamadermatol.2020.4383

This case series study of patients with granulomatous cheilitis at a tertiary referral center seeks to better describe the demographic characteristics, presenting features, associated disorders, and response to treatment of granulomatous cheilitis.

Accuracy and Cost-effectiveness of a Telemedicine Triage Initiative for Patients With Suspected Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis

Abstract Full Text
JAMA Dermatol. 2021;157(1):114-115. doi:10.1001/jamadermatol.2020.4490

This retrospective analysis assesses triage accuracy and transportation costs associated with implementation of a multidisciplinary store-and-forward telemedicine triage system for patients with suspected Stevens-Johnson syndrome and toxic epidermal necrolysis.

Pain Severity and Management of Hidradenitis Suppurativa at US Emergency Department Visits

Abstract Full Text
JAMA Dermatol. 2021;157(1):115-117. doi:10.1001/jamadermatol.2020.4494

This repeated cross-sectional study compares pain severity and rates of prescriptions for opioids in emergency department visits for hidradenitis suppurative with those in visits for atopic dermatitis or psoriasis.

Spectrum of Nail Sequelae in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

Abstract Full Text
JAMA Dermatol. 2021;157(1):117-119. doi:10.1001/jamadermatol.2020.4664

This case series documents the incidence of various nail changes as sequalae to Stevens-Johnson syndrome/toxic epidermal necrolysis.

Observation

Fibroblast Growth Factor Receptor Inhibitors and Nonuremic Calciphylaxis

Abstract Full Text
JAMA Dermatol. 2021;157(1):119-121. doi:10.1001/jamadermatol.2020.4076

This case report describes a woman in her 70s with type 2 diabetes, hypertension, idiopathic thrombocytopenia, and metastatic cholangiocarcinoma with an fibroblast growth factor receptor 2 translocation.

Use of Topical Sirolimus (Rapamycin) for Treating Confluent and Reticulated Papillomatosis

Abstract Full Text
JAMA Dermatol. 2021;157(1):121-123. doi:10.1001/jamadermatol.2020.4083

This case report describes an adolescent male with a history of prediabetes and obesity who presented with a diagnosis of confluent and reticulated papillomatosis with features of acanthosis nigricans.

Comment & Response

Association Between Early Severe Cardiovascular Events and Ustekinumab Treatment?

Abstract Full Text
JAMA Dermatol. 2021;157(1):123. doi:10.1001/jamadermatol.2020.4456

Association Between Early Severe Cardiovascular Events and Ustekinumab Treatment?—Reply

Abstract Full Text
JAMA Dermatol. 2021;157(1):123-124. doi:10.1001/jamadermatol.2020.4457
Correction

Transposed Author Names

Abstract Full Text
free access
JAMA Dermatol. 2021;157(1):124. doi:10.1001/jamadermatol.2020.4709

Errors in the Abstract, Introduction, Methods, and Discussion Sections

Abstract Full Text
free access
JAMA Dermatol. 2021;157(1):124. doi:10.1001/jamadermatol.2020.5204
JAMA Dermatology Masthead

JAMA Dermatology

Abstract Full Text
free access
JAMA Dermatol. 2021;157(1):19. doi:10.1001/jamadermatol.2020.3854
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