This cohort study assesses the performance of a prognostic survival model derived from randomized clinical trial data when the model is applied to real-world data from the electronic health records of patients with metastatic castration-resistant prostate cancer.
This cohort study examines temporal trends and risk factors associated with lower extremity amputation among veterans using Veterans Health Administration services.
This cross-sectional study provides an up-to-date assessment of the levels of and changes in knowledge of HIV/AIDs and its association with socioeconomic disparity among young women in low- and middle-income countries.
This cross-sectional study examines within-class changes in US wholesale drug prices for brand-name medications from 2015 to 2020.
This cross-sectional study uses data from the American Medical Association Physician Masterfile to examine physician density by specialty type across metropolitan and rural US counties from 2010 to 2017.
This cross-sectional study uses 2007-2012 data from the Association of American Medical Colleges’ Matriculating Student Questionnaire to evaluate student factors and academic outcomes associated with taking a leave of absence from medical school.
This cross-sectional study examines primary care physicians’ frequency of attention switching associated with electronic inbox work and identifies potentially modifiable factors associated with attention switching and inbox work duration.
This cross-sectional study compares the rate at which patients who are deaf are offered primary care medical or dental appointments with the rate at which appointments are offered to patients who can hear.
This cohort study evaluates whether the Affordable Care Act’s increase in Medicaid fees to Medicare levels for primary care practitioners was associated with increases in primary care visits for dual-eligible Medicare and Medicaid beneficiaries.
This case-control study examines the demographic variables, comorbidities, exposure to obstructive sleep apnea, and obstructive sleep apnea therapies in adult men with or without an infertility diagnosis.
This cohort study evaluates the prevalence of metastasis sites for clear cell, papillary, and chromophobe renal cell carcinoma (RCC) and examines the association between site of metastasis and overall survival.
This survey study examines the frequency of and reasons for reported forgone care among US adults during the COVID-19 pandemic.
This cross-sectional study assesses trends in suicide-related internet search rates in the early stages of the COVID-19 pandemic in the US.
This cohort study evaluates the association between the coronavirus disease 2019 (COVID-19) stay-at-home orders and suicide deaths in Massachusetts.
This cross-sectional study describes the differential associations of the coronavirus disease 2019 (COVID-19) pandemic with opioid-related overdoses among racial/ethnic groups in Philadelphia, Pennsylvania.
This cross-sectional study uses data from smartphone users to examine the association of government-mandated closures and restrictions with aggregate mobility and the association of changes in mobility with confirmed SARS-CoV-2 infections in Nigeria.
This cross-sectional study examines city-level data from the 30 most populous US cities regarding all-cause mortality rates and racial inequities within cities and seeks to determine whether these measures changed during the past decade.
This cross-sectional ecological analysis quantifies the association of economic inequality, racial/ethnic composition, political factors, and state health care policy with the incidence and mortality burden associated with coronavirus disease 2019 (COVID-19) at the US county level.
This cohort study examines the association of nutritional support with mortality rates among hospitalized patients with malnutrition in Switzerland.
This prognostic study compares performances between pathologists and a deep learning model to quantify percent global glomerulosclerosis on images of kidney biopsy specimens and assesses the potential benefit of the model on donor kidney discard rates.
This survey study assesses perceptions of and motivations for uterus transplant among transgender women and explores their willingness to undergo the procedure.
This survey study examines factors associated with motivation to use and distribute self-tests for COVID-19 infection among US adults.
This cohort study examines the association of patient caseload and demand with mortality among patients with coronavirus disease 2019 (COVID-19) in US Veterans Affairs (VA) intensive care units.
This secondary analysis of the Evaluating Adverse Events in a Global Smoking Cessation Study (EAGLES) randomized clinical trial compares the pharmacotherapy efficacy of varenicline, bupropion, and nicotine replacement therapy in quitting smoking for Black vs White US smokers.
This economic evaluation analyzes the cost-effectiveness of pembrolizumab as a second-line treatment in patients with advanced hepatocellular carcinoma.
This cohort study uses interrupted time series regression to assess the association between changes in race/ethnicity data collection in the American Medical College Application System survey and trends in applicants, matriculants, and graduates self-reporting as American Indian and Alaska Native.
This mendelian randomization study evaluates summary statistics from genome-wide associations involving more than 1 million individuals to assess whether there are differential associations between genetic liability to smoking and risk of coronary artery disease, peripheral artery disease, and large-artery stroke.
This cohort study describes the burden of coronavirus disease 2019 among people detained by US Immigration and Customs Enforcement compared with the US population.
This nonrandomized controlled trial uses data from a single tertiary care center in the US to investigate the accuracy of magnetic resonance imaging (MRI)–guided biopsy compared with surgical resection for assessing pathologic complete response after neoadjuvant chemotherapy in patients with breast cancer.
This cohort study investigates the association of aspirin use with risk of developing new cancers and site-specific cancer-associated survival in bladder, breast, esophageal, gastric, pancreatic, and uterine cancers.
This cohort study examines trajectories of cognitive function and their associations with cognitive reserve, physical health, and postmortem levels of neuropathology associated with Alzheimer disease in Dutch centenarians.
This cross-sectional study develops and validates a method to more precisely quantify dose intensity of hypertension treatment using only health system administrative pharmacy fill data.
This cohort study examines which patient and facility factors in the US Department of Veterans Affairs health care system are associated with dialysis approaches and outcomes.
This cross-sectional study examines structural brain associations with CD4+ T-cell count and viral load in HIV-positive individuals taking and not taking combination antiretroviral therapy.
This cohort study examines interruptions by residents and faculty discussants during residency teaching conferences by gender.
This randomized clinical trial assesses whether injection-site pain and reactogenicity are noninferior in trivalent adjuvanted inactivated influenza vaccine (aIIV3) compared with trivalent high-dose inactivated influenza vaccine (HD-IIV3) among adults aged 65 years and older.
This cohort study assesses the association between estimated glomerular filtration rate (eGFR) calculated with vs without a coefficient for race and time to achievement of an eGFR less than 20 mL/min/1.73 m2.
This survey study evaluates the current state of the completeness, timeliness, and usability of information sharing, and identifies characteristics associated with better sharing, to support patient care transitions between hospitals and skilled nursing facilities.
This qualitative study surveyed physicians and other health professionals working in oncology to determine the perceived advantages and disadvantages of telehealth video visits in cancer care.
This quality improvement study assesses referral rates for cardiac rehabilitation after a default opt-out option is added to the decision pathway in the electronic medical record.
This randomized clinical trial evaluates the efficacy and safety of bimagrumab on body composition and glycemic control in adults with type 2 diabetes and overweight or obesity.
This cohort study uses data from the New Zealand Integrated Data Infrastructure database to examine the association of mental disorders with subsequent physical diseases and mortality among the New Zealand population over a 30-year observation period.
This survey study identifies the minimum effectiveness patients with type 1 and type 2 diabetes report they require to adopt 36 different remote digital diabetes monitoring scenarios.
This economic evaluation assesses the cost-effectiveness of the addition of prostate radiation therapy to androgen deprivation therapy for men with low-volume metastatic hormone-sensitive prostate cancer.
This quality improvement study assesses the association of automated text messaging follow-up with the patient response rate after same-day surgery.
This cohort study compares the findings of combined pertuzumab, trastuzumab, and docetaxel therapy in women with metastatic breast cancer with those in the CLEOPATRA trial.
This randomized clinical trial assessed whether controlled exposure to e-cigarette puffs with salt vs free-base nicotine formulations improved the appeal and sensory experience of vaping among adult current nicotine or tobacco product users.
This cohort study investigates the associations of race, socioeconomic factors, and treatment characteristics with overall survival (OS) among patients with limited-stage small cell lung cancer (SCLC).
This survey study compared parents who chose to participate in a neonatal clinical trial with those who declined, assessing differences in demographic characteristics, opinions on the severity of their child’s medical condition, and levels of trust in medical researchers.
This cross-sectional study assesses the changes associated with the revised US Preventive Services Task Force guideline with lung cancer screening eligibility among female, Black, and Hispanic populations using a large nationwide survey.
This cohort study uses national register data to analyze whether people with ASD have higher rates of suicide attempt and suicide compared with people without ASD, identify potential risk factors for suicide attempts and suicide among those with ASD, and examine associations with comorbid disorders.
This economic evaluation uses Markov modeling to identify and compare the cost and utility of doublet and standard treatments for patients with BRAF V600E variant colorectal cancer.
This cross-sectional study examines the representation of darker skin phenotypes in tools used by students in preparation for medical licensure testing.
This randomized clinical trial examined outcomes of inguinal hernia surgery performed by associate clinicians vs nonspecialist medical doctors among men in Sierra Leone.
This cohort study evaluates the association between the time from the return of spontaneous circulation to electrocardiogram (ECG) acquisition and the diagnostic accuracy of ECG for ST-segment elevation myocardial infarction in patients who experience out-of-hospital cardiac arrest.
This cohort study assesses whether emergency medical transportation by helicopter vs by ground is associated with differences in mortality among patients in Denmark.
This quality improvement study assess a systematic recruitment initiative aimed at ensuring adequate matriculation of women and underrepresented racial and ethnic groups in a general cardiology fellowship.
This serial cross-sectional study examines online crowdsourced fundraising for US health care costs from 2010 to 2018 and evaluates whether there are trends by medical condition and geographic distribution.
This cohort study estimates the proportion of recipients of durable left ventricular assist devices (LVADs) who are ineligible for clinical trial participation and assesses whether an association exists between ineligibility and mortality.
This cohort study examines the risk of all-cause and noncommunicable disease deaths among young adults born preterm and early term in 4 Nordic countries.
This cohort study examines the association of advanced glycation end products and their receptor with dementia in the general Dutch population.
This cohort study assesses the association between radiotherapy and the risk of individual types of second gynecological malignant neoplasms in patients with rectal cancer and estimates survival outcomes for patients with secondary cancers.
This cohort study of hospitalized patients uses a machine learning model to predict the risk of iatrogenic hypoglycemia within 24 hours after blood glucose measurement during hospitalization.
This cross-sectional study uses Lorenz curves as a metric for quantifying racial inequities in coronavirus disease 2019 (COVID-19) testing.
This decision analytical model assesses the proportion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmissions in the community that likely occur from persons without symptoms.
This cohort study examines the association between age at exposure to household dysfunction during childhood and adolescence and outcomes in early adulthood.
This cross-sectional study examines the associations between parental and adolescent prescription opioid medical use and misuse among parent and adolescent dyads in the National Survey on Drug Use and Health.
This cohort study compares the numbers of endoscopic examinations for gastric cancer screening over quarters of a calendar year with rates of gastric cancer diagnosed during those periods.
This cross-sectional study maps a coronavirus research question to illustrate the overlap and shortcomings of the evidence syntheses in this area.
This randomized clinical trial examines how a machine learning model trained to identify out-of-hospital cardiac arrest and alert dispatchers during emergency calls affected the recognition of and response to out-of-hospital cardiac arrests.
This cross-sectional study uses Massachusetts medical licensure and business registration records to examine the proportion of physician-founded companies and the types of businesses started.
This cohort study uses data from tertiary frontotemporal dementia research clinics across Europe and Canada to assess the frequency and severity of behavioral symptoms and their progression in different forms of genetic frontotemporal dementia.
This cohort study uses data from the Korean National Health Insurance System database to investigate whether female reproductive factors are associated with fractures among postmenopausal women in Korea.
This cohort study of a large nationwide database of Chinese adults assesses the association between dietary niacin intake and the risk of new-onset hypertension.
This mixed-methods study explores individual and workplace factors that are associated with surgical trainees’ well-being, differences by gender identity, and end-user perceptions of experience.
This cross-sectional study compares trends in out-of-hospital cardiac arrests and fatalities in the Detroit area during the COVID-19 pandemic with year-earlier events for the same period.
This survey study examines knowledge, risk perceptions, and behavioral intentions among survey respondents exposed to different types of COVID-19 prevalence maps.
This meta-analysis assesses differential brain responses to noxious stimuli in patients with chronic pain using functional magnetic resonance imaging while adhering to current best practices for neuroimaging meta-analyses.
This cross-sectional study uses data from 3 state agencies merging comprehensive insurance claims with income eligibility data for Colorado Medicaid expansion and Marketplace enrollees to investigate health care utilization, cost, and quality between public and private health insurance for low-income adults.
This cross-sectional study assesses the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease burden in the US, using surveillance data and seroprevalence surveys to estimate the number of SARS-CoV-2 infections, symptomatic infections, hospitalizations, and deaths through November 15, 2020.
This cross-sectional analysis of compares rates of ocular sequelae in antibody-positive survivors of Ebola virus disease and antibody-negative close contacts.
This cohort study assesses the use of a deep learning model for predicting occult peritoneal metastasis based on preoperative computed tomographic images in patients with gastric cancer.
This cohort study evaluates whether African American individuals with sickle cell trait have a higher incidence of myocardial infarction or composite coronary heart disease outcomes compared with those without sickle cell trait.
This modeling study uses 2 climate models and under 2 air pollutant emission scenarios to model the associations between future changes in climate, air quality, and human health.
This qualitative study attempts to derive patient-defined adverse cardiovascular and noncardiovascular events through a modified Delphi consensus-based process involving panel discussions with patients and their caregivers and clinicians.
This survey study describes individuals’ concerns regarding violence in the context of the coronavirus disease 2019 (COVID-19) pandemic, experiences of pandemic-related unfair treatment, prevalence of and reasons for firearm acquisition, and changes in firearm storage practices due to the pandemic.
This ecological study evaluates the public mobility and social media attention associated with COVID-19 spread and societal interventions from February 15 to June 14, 2020, in Denmark and Sweden.
This case-control study uses magnetic resonance imaging and spectroscopy to evaluate the association between treatment with recombinant adeno-associated virus serotype rh74 (rAAVrh74) and muscle quality in children with Duchenne muscular dystrophy.
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